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    Odds Increase for Approval of Incyte's Myelofibrosis Drug

    Wed, 09/29/2010 - 05:28 EDT - Seeking Alpha
    • INCY
    • Prohost Biotech

    Prohost Biotech submits:We will not lose our breath running after all the news posted about the biotech industry. We will restrict our selection to the most significant announcements. While there is good news about biotech firms’ breakthroughs, it is lost amid the mass of articles announcing or assessing the firms’ finances, routine events, meetings and plans (that may or may not come to pass), in addition to results from very early-phase trials that mean very little at their stage. The excessive amount of news has become confusing, especially since many are not mere news, but opinionated articles that contradict each other’s opinions with or without relevance.A case in point, Dendreon’s (DNDN) Provenge, the firm’s prostate cancer vaccine has just reached the market and yet, we are bombarded every day with articles, some highlighting the vaccine while others doubting its value. Each group has its backers of physicians, researchers and specialized analysts. It is obvious that what is meant to be read and believed is not about the vaccine’s efficacy or the lack of it, but about the stock price. Since the FDA approval of Provenge, DNDN has tremendously risen and risen again on good news about reimbursement, then on news that a prostate cancer drug developed by another firm has failed. The negative investors are finding it an opportunity to short the stock and advocate not buying it. Those who are positive on DNDN are advocating the opposite. One of these two opposing groups will win in the short term. We have no way to pinpoint the winning or losing group. The whole thing has come down to gambling, which is not our business.Complete Story »

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    Related

    • Dendreon Redux

      Michael Shulman submits: I clearly ruffled some feathers with my write-up of Dendreon (DNDN), mostly those of Dendreon bulls, many of them traders who know little if anything about the company. They accused me of everything from being a moron to a child molester because I said an approval for Provenge was not a slam dunk. So let me make myself very clear.

    • Good News for Dendreon's Provenge

      Saul Kerpelman submits:Dendreon (DNDN) made a big splash this past year by getting FDA approval for the first active cellular immuno-therapy for cancer. Its lead product Provenge trains the immune systems of men with advanced prostate cancer to recognize cancer cells as foreign and kill them.

    • Dendreon's Boring Q1 Results

      By William Meyers: Dendreon (DNDN) investors (and speculators) have become used to wild price swings. In the early years, these depended on opinions about whether the FDA would give marketing approval for Provenge for prostate cancer. After FDA approval came after years of delay, we had overly-optimistic forward-looking guidance on how fast Provenge sales would ramp from Dendreon management, and wildly optimistic forecasts by bullish analysts.

    • Dendreon: Where Do Things Stand On Provenge Reimbursement?

      By Theodore Cohen:There is no question that Dendreon (DNDN) has faced many hurdles in bringing Provenge, its immunotherapeutic treatment for end stage prostate cancer, to market. Among them were the many barriers thrown in its path by the FDA and CMS, to name a few. And now, with its treatment on the market, questions related to doctor reimbursement and the qualification of patients seeking treatment remain of paramount concern to doctors and investors alike.

    • Doctor Who Is a Provenge Fan Says Reimbursement Is a Risk

      By Pharmalot: Earlier this week, Dendreon (DNDN) shocked investors by scrapping its 2011 sales forecast for its controversial and innovate Provenge prostate cancer vaccine after disclosing that sales were slower than planned. The stated reason was that many doctors, particularly those in smaller settings, were slow to adopt the $93,000 vaccine since they had to wait for reimbursement.

    • Immunocellular Therapeutics: Ushering In the Next Generation of Cancer Immunotherapies

      VFC submits: It was an historic day for the future of cancer treatment when the FDA approved Dendreon's (DNDN) Provenge for the treatment of prostate cancer just over one year ago. It opened the doors to a new age in the treatment of cancer, and shareholders delighted alongside victims of prostate cancer -- patients who had long been looking for an alternative to the harsh side effects of chemotherapy and radiation treatments.

    • ImmunoCellular Therapeutics' Resemblance to Dendreon - At a Fraction of the Cost

      Edward Stevenson submits:Less than two years ago, Dendreon's (DNDN) Provenge, an active cellular immunotherapy treatment for prostate cancer, was proven to prolong the survival rate of patients receiving the remedy in a series of controlled clinical trials. According to the company's data:

    • Dendreon’s (DNDN) Cancer Vaccine Faces Impact of Medicare Reimbursement

      The Financial Times is reporting that Dendreon Corporation’s (DNDN) prostate cancer vaccine Provenge will be impacted by Medicare reimbursement delays.

    • Dendreon: Yes, It Got FDA Approval, But Here's What It Did Wrong

      Michael Shulman submits: Dendreon (DNDN) investors – and traders long the stock – got what they wanted yesterday with the FDA approval of their treatment for advanced metastatic prostate cancer, Provenge.

    • Dendreon: To Short or Not to Short?

      Michael Shulman submits: I "made my bones" with a bullish and complicated call on Dendreon (DNDN) several years ago, predicting it would get a thumbs up from an FDA panel for its advanced prostate cancer treatment Provenge. Only one other biotech analyst with a public audience agreed with me - and the panel, sure enough, voted yes.

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