Excess Risk of Cardiac Events Associated with Dabigatran

By Zami Aberman: Editor's Note: Author is the CEO of Pluristem

Boehringer Ingelheim is starting to inform physicians about a new contraindication for its oral anticoagulant drug Pradaxa (dabigatran). The company has told investigators in trials utilizing dabigatran that it will shortly be sending a "Dear Doctor Letter," also known as a Direct Healthcare Professional Communication (DHPC), to healthcare professionals. The [...]

Since its approval in the United States in October 2010 dabigatran (Pradaxa) has been prescribed 3.2 million times to more than 600,000 patients with nonvalvular atrial fibrillation (AF), according to its manufacturer, Boehringer Ingelheim. The company also announced that, based on the pivotal RE-LY trial, the ?Clinical Studies? section of the drug?s prescribing information now ...

In May Of 2010, I published a series of reader contributions on the cruise line industry as well some proprietary research on a paricular company in said industry - Royal Carribearn Cruise Lines. The consistent, globally synchronized flood of money totally distorted market pricing and risk in public equities - thus often distorted practicaly applicability

Severe blood conservation in conjunction with cardiac surgery is not associated with long-term adverse consequences, according to a new study published in Archives of Internal Medicine.  Investigators from the Cleveland Clinic and the NHLBI compared 322 patients who were Jehovan's Witnesses with an equal number of matched controls. Due to [...]

A new meta-analysis sheds additional light on the cardiovascular risk of NSAIDs as used in the real world, including low doses of the most popular drugs, over short periods, and in low-risk populations. In a paper published online in??PLoS Medicine,??Patricia McGettigan and David Henry analyzed data from 30 case-control studies including 184,946 CV events and ...

By Iggy Igette: According to the American Heart Association, approximately 715,000 Americans suffered heart attacks in 2012. Of these, 525,000 were first-time heart attacks and 190,000 occurred in people who had already experienced a heart attack.