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    Dendreon: Righting The Ship

    Fri, 09/09/2011 - 11:27 EDT - Seeking Alpha
    • DNDN
    • Saul Kerpelman

    By Saul Kerpelman:
    Dendreon Corporation (DNDN) held a very interesting conference call yesterday evening to outline its restructuring to deal with the slower than predicted launch of its newly approved cancer treatment, Provenge for late-stage prostate cancer.

    Provenge trains the patient's immune system to fight cancer, and has been hailed as a major cancer breakthrough--the first cancer immunotherapy approved by the FDA.

    The company had consistently guided for $350-$400 million in revenues for 2011 and the shares tanked 67% after its August 3 conference call pulling that guidance after slower than expected uptake, which the company said was related to doctors' fears about reimbursement.
    It's obvious there was nothing the company could possibly say that would have instantly regained the lost ground for the share price. That is undoubtedly going to be a multi-quarter process as the company reestablishes its credibility with the Market, but all in all the call was very informativeComplete Story »

    • Original article
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    Related

    • Dendreon: Profits Ahead as Provenge Gets Reimbursement Approval From Medicare

      By Saul Kerpelman: Shares of Dendreon Corporation (DNDN) have plummeted since its last earnings conference call this past August 3.

    • Dendreon: The Challenge Of Misinformation

      By Saul Kerpelman:One of the challenges facing Dendreon Corporation (DNDN) as it attempts to recover from its recent slide is the need to respond to and correct the virtual torrent of misinformation that has attended the Provenge story.

    • High Risk Trading With Dendreon

      By Osman Gulseven:Investing in Dendreon (DNDN) is a risky business. The company currently relies only on one product: Provenge. While Dendreon has a few drug candidates in the pipeline, the timeline for FDA submission is uncertain.

    • Dendreon: Market Mania In Action

      By Saul Kerpelman:In a matter of mere months Dendreon Corporation (DNDN) has gone from being the Darling of the Biotech World, with every small biotech avidly hoping and striving to be "The Next Dendreon"--even as Dendreon's advocates had long hoped for it to be the fabled "Next Amgen"--to being a pariah whose shares have lost roughly 80% of their value.

    • Immunotherapy Comes Of Age At ASCO 2012

      By The Swiss Trader:Until just recently, immunotherapy (or stimulation of the immune system to treat disease) was regarded as an ill-conceived approach in cancer drug development. Many scientists and investors did not consider immunotherapy treatment to be a legitimate area of cancer research. The skepticism was not totally unfounded as there had been years of failures, such as those from CancerVax, IDM, and Cell Genesys to name a few.

    • Overcoming The Challenges Of Cell-Based Cancer Immunotherapy

      By Andrew J. Norris: Unlike chemotherapy, which directly attacks cancer cells, immunotherapy stimulates a patient's immune system to attack tumors and ultimately prolong survival. Autologous cellular immunotherapy, such as Dendreon's (DNDN) sipuleucel-T (Provenge), uses patients' own immune cells to defend against cancer as these cells are best known as nature's adjuvants and are very powerful in eliciting an immune response.

    • Dendreon: Following Up On Market Mania

      By Saul Kerpelman:Back on November 7, 2011, I wrote about Dendreon Corporation (DNDN) and what I called the "Market Mania" surrounding its "slow" launch of Provenge, the first FDA approved immunotherapy for the treatment of advanced prostate cancer.

    • Dendreon's Earnings Announcement Has Investors Looking For A Sectorwide Turnaround

      By VFC: When the entire biotechnology sector looked to have taken a downturn all at the same time a couple of months ago, many pointed fingers at Dendreon (DNDN), whose shares plummeted after announcing a complete revision of 2011 sales guidance for Provenge.

    • Thursday Options Brief: DNDN, EW, IO & CCI

      Andrew Wilkinson submits:

    • Beyond Provenge: Dendreon Is Too Expensive for Value, Growth Investors

      Analytical Chemist submits:Dendreon (DNDN) is not an attractive stock for a value investor to buy right now. It’s also not attractive for growth investors who value any margin of safety. While Dendreon has a remarkable technology approved in its Provenge treatment for advanced prostate cancer, its sales and earnings prospects based on this treatment are not enough to justify its current stock price.

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